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Evidence Reviews for Health & Social Care

What is data analysis?

Data Analysis breaks down information. 

The purpose is to examine, interpret and draw conclusions from data.

Data Analysis - quantitative

Quantitative data analysis involves processing and interpreting numerical data to draw meaningful conclusions. Here are some key steps in quantitative data analysis:

  1. Data Preparation:

    • Clean and organize the data.
    • Handle missing values and outliers.
    • Transform variables if needed (e.g., normalization, standardization).
  2. Descriptive Statistics:

    • Calculate measures like mean, median, mode, and standard deviation.
    • Create histograms, box plots, or scatter plots to visualize data distributions.
  3. Inferential Statistics:

    • Perform hypothesis tests (e.g., t-tests, ANOVA) to compare groups.
    • Calculate confidence intervals.
    • Assess relationships (correlation, regression).
  4. Statistical Software:

    • Use tools like R, Python (with libraries like pandas, numpy, and scipy), or SPSS for analysis.

META-ANALYSIS

 When conducting data analysis for a meta-analysis, follow these steps:

  1. Data Extraction:

    • Collect relevant data from each study, including effect sizes, sample sizes, and other relevant statistics.
    • Ensure consistency in data extraction across studies.
  2. Effect Size Calculation:

    • Compute effect sizes (e.g., Cohen’s d, odds ratio, correlation coefficient) for each study.
    • Standardize effect sizes to facilitate comparison.
  3. Forest Plot:

    • Create a forest plot to visualize effect sizes and confidence intervals for each study.
    • Identify the overall effect size (pooled estimate) and its precision.
  4. Heterogeneity Assessment:

    • Evaluate heterogeneity among studies using statistical tests (e.g., Cochran’s Q, I²).
    • High heterogeneity may require subgroup analyses or sensitivity analyses.
  5. Fixed-Effect or Random-Effects Model:

    • Choose an appropriate model (fixed-effect or random-effects) based on heterogeneity.
    • Fixed-effect assumes a common effect size, while random-effects accounts for variability.
  6. Publication Bias:

    • Assess publication bias using funnel plots or statistical tests (e.g., Egger’s test).
    • Adjust for bias if necessary.

Remember that meta-analysis requires careful consideration of study quality, study design, and statistical assumptions.

https://training.cochrane.org/handbook/current/chapter-10

 

NARRATIVE SYNTHESIS

Data analysis for narrative synthesis involves collating and organizing study findings from different studies in a review. Unlike meta-analysis, which uses statistical methods, narrative synthesis relies on textual descriptions to integrate results. Here are some key steps:

  1. Collate Findings: Describe the main features of each study, including context, validity, and differences in characteristics.

  2. Structured Tabulation: Use tables and graphs to display results and highlight variations across studies.

  3. Transparency: Promote transparency by justifying decisions and pre-specifying the synthesis approach in the review protocol

https://cccrg.cochrane.org/sites/cccrg.cochrane.org/files/uploads/AnalysisRestyled.pdf

Thematic Analysis - qualitative

Braun and Clarke (2006) thematic analysis method is a process consisting of six steps:

  1. becoming familiar with the data
  2. generating codes
  3. generating themes
  4. reviewing themes
  5. defining and naming themes
  6. locating exemplars

Read:
Braun, V. and Clarke, V. (2006) ‘Using thematic analysis in psychology’, Qualitative research in psychology, 3(2), pp. 77–101. Available at: https://doi.org/10.1191/1478088706qp063oa.

Watch:

Watch these youtube lecture videos on Thematic Analysis, presented by Victoria Clarke in 2021:
Thematic Analysis Part 1: What is Thematic Analysis?
Thematic Analysis Part 2: Thematic Analysis is uniquely flexible
Thematic Analysis Part 3: Six phases of reflective thematic analysis
Thematic Analysis Part 4: Avoiding common problems